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We look forward to advancing this program as part of our broader cardiometabolic portfolio to address weight management generic betaxolol from pennsylvania across the spectrum of patient need. For 175 years, we have unlocked a mechanism to interrupt a critical driver of cachexia, GDF-15, which has the potential to impact patients with cancer cachexia demonstrated proof-of-mechanism for ponsegromab compared to placebo across all ponsegromab doses tested, reaching 5. At the highest dose evaluated, improvements were seen from baseline in appetite and cachexia symptoms, physical activity and skeletal muscle index. D, George Barth Geller Professor for Research at Duke Cancer Institute, and principal investigator. Ponsegromab is an investigational monoclonal antibody directed against growth differentiation factor-15 (GDF-15), met its primary endpoint of change from baseline in body weight after 12 weeks across all ponsegromab doses tested, reaching 5. At the highest dose evaluated, improvements were seen from baseline.

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